Walker Downey & Associates, Inc.
Quantitative Morphometric Analysis (QMA)
More and more scientists are searching for objective data, for parameters which permit the quantitation of the deformation of a structure, whether it is a cell, subcell organ or tissue. Objective data are continuously being sought so that a diagnosis may be repeatable, the margin of subjective impression may be reduced and at least in continuous lesions, any changes which occur may be defined. Morphometry in pathology is the process of measuring the shape, area, and volumes of tissue structures, an important tool for the quantitative analysis of histologic data. Information derived from morphometric studies provides a more precise assessment of the physiologic or pathologic state than that which can be derived from purely descriptive means. Histological slides can be evaluated morphometrically when the tissue type is appropriate with distinct borders between the objects to be measured. Using morphometric analysis on tissues without clear boundaries can result in more experimental error than is associated with the subjective grading of lesions.
Contact us at info@walkerdowney.com to discuss how our QMA may help your product safety and development programs.